The vision of the Centre of Molecular Inflammation Research (CEMIR) is to lay the foundation for identifying new therapeutic targets and developing new diagnostic tools for inflammatory diseases.
This will happen through an integrated 10-year programme of research and research training in molecular innate immune responses. CEMIR was established on 10. June 2013 as a Centre of Excellence (SFF) appointed by the Research Council of Norway.
Inflammation is a host response that is triggered by infection and tissue injury. A controlled inflammatory response is needed to fight infections and to heal wounds, but it can become detrimental if it is dysregulated as seen in chronic inflammatory disorders like cardiovascular disease, diabetes, Alzheimer's disease, inflammatory bowel disease, obesity, cancer, and others.
Drawing on major recent advances in the field of innate immunity and cell biology, CEMIR's research programme will detail the molecular and cell biological principles for initiation and regulation of inflammatory responses through the use of basic research, in vitro- and in vivo models and unique biobanks. The localisation of CEMIR in an integrated University hospital environment will facilitate translational research on human disease.